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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 04th March 2024 Vol. No. 13 ; Issue No.620
Publications

1. Sengupta S, Biswas M, Gandhi KA, Gupta SK, Gera PB, Gota V, Sonawane A (2024). Preclinical evaluation of engineered L-asparaginase variants to improve the treatment of Acute Lymphoblastic Leukemia.43:101909 Translational Oncology.

2. Shetty T, Joshi P, Talole S, Nair S, Chaturvedi P (2024). Factors affecting drain output in oral carcinoma. Journal of Maxillofacial and Oral Surgery

3. Srinivasan S, Keerthivasagam S, Kumar S, Puri A (2024). ASO Author Reflections: Utilizing surveillance imaging techniques for detecting recurrences in patients with extremity sarcomas. Annals of Surgical Oncology. 31(3):2063-2064.

4. Qureshi S, Reddy S, Smriti V, Baheti A, Shah S, Channaswamy G, Prasad M, Parambil B, Gollamudi V, Panjwai P, Ramadwar M, Amin N, Kembhavi S (2024). Impact of surgical timing (primary, delayed, or second look) on surgical morbidity and outcomes in Malignant Germ Cell Tumor of the Ovary in children. Journal of Pediatric Surgery

5. Rao AR, Noronha V, Ramaswamy A, Kumar A, Pillai A, Sehgal A, Castelino R, Dhekale R, Jagtap P, Tripathi V, Satamkar S, Krishnamurthy J, Mahajan S, Daptardar A, Sonkusare L, Deodhar J, Ansari N, Vagal M, Mahajan P, Timmanpyati S, Nookala M, Chitre A, Kapoor A, Gota V, Banavali S, Badwe RA, Prabhash K. Assessing frailty in older Indian patients before cancer treatment: Comparative analysis of three scales and their implications for overall survival. Journal of Geriatric Oncology. 15(3):101736

6. Wadasadawala T, Joshi S, Rath S, Popat P, Sahay A, Gulia S, Bhargava P, Krishnamurthy R, Hoysal D, Shah J, Engineer M, Bajpai J, Kothari B, Pathak R, Jaiswal D, Desai S, Shet T, Patil A, Pai T, Haria P, Katdare A, Chauhan S, Siddique S, Vanmali V, Hawaldar R, Gupta S, Sarin R, Badwe R. Tata memorial centre evidence based management of breast cancer. Indian Journal of Cancer. 61(Suppl 1):S52-S79

7. Puranik AD, Choudhury S, Ghosh S, Dev ID, Ramchandani V, Uppal A, Bhosale V, Palsapure A, Rungta R, Pandey R, Khatri S, George G, Satamwar Y, Maske R, Agrawal A, Shah S, Purandare NC, Rangarajan V. Tata memorial centre evidence based use of nuclear medicine diagnostic and treatment modalities in cancer. Indian Journal of Cancer. 61(Suppl 1):S1-S28.

8. Saklani A, Kazi M, Desouza A, Sharma A, Engineer R, Krishnatry R, Gudi S, Ostwal V, Ramaswamy A, Dhanwat A, Bhargava P, Mehta S, Sundaram S, Kale A, Goel M, Patkar S, Vartey G, Kulkarni S, Baheti A, Ankathi S, Haria P, Katdare A, Choudhari A, Ramadwar M, Menon M, Patil P. Tata memorial centre evidence based management of colorectal cancer. Indian Journal of Cancer. 61(Suppl 1):S29-S51.

Thesis
Saket Vatsa Mishra. 2024. Understanding the molecular mechanism of leukemia resistance using cellular and pre-clinical model of leukemia resistance. (LIFE09201604017) (Guide: Dr.Shilpee Dutt)

Site of the Week

GeneWise compares a protein sequence to a genomic DNA sequence, allowing for introns and frameshifting errors.

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Interesting Reads

Hardaker EL, Sanseviero E, Karmokar A, Taylor D, Milo M, Michaloglou C, Hughes A, Mai M, King M, Solanki A, Magiera L, Miragaia R, Kar G, Standifer N, Surace M, Gill S, Peter A, Talbot S, Tohumeken S, Fryer H, Mostafa A, Mulgrew K, Lam C, Hoffmann S, Sutton D, Carnevalli L, Calero-Nieto FJ, Jones GN, Pierce AJ, Wilson Z, Campbell D, Nyoni L, Martins CP, Baker T, Serrano de Almeida G, Ramlaoui Z, Bidar A, Phillips B, Boland J, Iyer S, Barrett JC, Loembé AB, Fuchs SY, Duvvuri U, Lou PJ, Nance MA, Gomez Roca CA, Cadogan E, Critichlow SE, Fawell S, Cobbold M, Dean E, Valge-Archer V, Lau A, Gabrilovich DI, Barry ST. The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment. Nat Commun. 15(1): 1700, 2024.

Video of the Week
Scalable Diet and Exercise Interventions for Cancer Prevention and Control
Upcoming Events
India Breast Meeting: Crystalizing Current Cancer Care

April 5 - 7, 2024

At Sir HN Reliance Foundation Hospital, Mumbai

AACR Annual Meeting 2024

April 5 - 10, 2024

At San Diego Convention Center San Diego, California

Cancer Immunotherapy: Beyond Immune Checkpoint Blockade and Overcoming Resistance

March 17 - 20, 2024

At Fairmont Chateau Whistler, Whistler, BC, Canada

Do You Know?

In 2015, FDA approved talimogene laherparepvec (T-VEC) for the treatment of some patients with metastatic melanoma that cannot be surgically removed

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Cancer News
The Rs 100 pill: How Tata Memorial’s new drug will prevent cancer comeback

Financial Express, 28/02/2024

Dr Indraneel Mittra, the lead scientist behind the TMH research, explained how their experiments involving human breast cancer cells implanted in mice elucidated the impact of different cancer treatments on chromatin levels. Remarkably, a combination of resveratrol and copper...

ctDNA may guide who needs chemo after colorectal cancer surgery.

National Cancer Institute, 28/02/2024

In the study, the presence of fragments of genetic material that have escaped from tumors into the bloodstream, or circulating tumor DNA (ctDNA), seemed to predict which patients would benefit from the chemotherapy they receivedExit Disclaimer...

Scientists discover mucus allows young pancreatic cancer cells to grow but may also prevent a deadly transformation

MedicalXpress, 28/02/2024

The scientists broke down messy clumps of pancreatic tumors into individual cancer cells. From there, they could examine the unique differences between each pancreatic cancer type. And that's where mucus' role in cancer differentiation oozed into view...

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